Módulo 2 – Curso pós-graduado – VIH e Envelhecimento

Non-AIDS Defining Cancers Among HIV Infected People

The epidemiology of non-AIDS defining cancers among HIV infected patients

Key messages

  • The incidence of AIDS-defining cancers has been decrea- sing while the incidence of NADCs is increasing, mainly due to the increase of viral related NADCs incidence;
  • Cancer incidence among HIV patients is similar to that obser- ved in immunosuppressed transplant patients;
  • Overall mortality of HIV patients due to NADCs is increasing, as mortality due to other causes declines;
  • The severe immunodeficiency, impaired CD4+ restoration and older age may contribute to increased risk of NADCs, espe- cially infection-related malignancies;
  • The risk of NADCs may be minimized by treating HIV patients early, with maximally effective and well-tolerated drugs.
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